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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9A All Species: 26.67
Human Site: S253 Identified Species: 48.89
UniProt: O75110 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75110 NP_006036.1 1047 118583 S253 P P I S E S L S I E N T L W A
Chimpanzee Pan troglodytes XP_514727 875 98509 E107 V V L Y T G R E L R S V M N T
Rhesus Macaque Macaca mulatta XP_001098852 1044 118009 S250 P P I S E S L S I E N T L W A
Dog Lupus familis XP_534457 1043 118292 S249 P P I S E S L S I E N T L W A
Cat Felis silvestris
Mouse Mus musculus O70228 1047 118590 S253 P P I S E S L S I E N T L W A
Rat Rattus norvegicus XP_002726328 995 111897 R227 N F L G T F T R V N S D P P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509092 1116 127035 S322 P P V S E S L S I E N T L W A
Chicken Gallus gallus XP_417508 1115 125396 S321 P S V N E S L S I E N T L W A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 S300 P P I H E S L S I E N T L W A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 G461 Y S S E E S L G V D N T L W A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 G311 V S T Q D A L G I E N T L W A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 V237 N T E W A C G V S V Y T G N Q
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 D365 T S N P L S V D N T L W A N T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 97.8 97.4 N.A. 97.9 89.7 N.A. 90.2 89.5 N.A. 71.3 N.A. N.A. 54.3 N.A. 60.4
Protein Similarity: 100 83.5 98.2 98.2 N.A. 99.5 91.8 N.A. 92.2 91.5 N.A. 82.4 N.A. N.A. 66.8 N.A. 74.4
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 93.3 80 N.A. 93.3 N.A. N.A. 53.3 N.A. 53.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 20 N.A. 100 93.3 N.A. 93.3 N.A. N.A. 66.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 29 44.6 N.A.
Protein Similarity: N.A. N.A. N.A. 48.4 62.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 70 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 0 8 0 8 0 0 0 % D
% Glu: 0 0 8 8 62 0 0 8 0 62 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 8 8 16 0 0 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 39 0 0 0 0 0 62 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 16 0 8 0 70 0 8 0 8 0 70 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 16 0 8 8 0 0 0 0 8 8 70 0 0 24 0 % N
% Pro: 54 47 0 8 0 0 0 0 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 8 8 0 8 0 0 0 0 0 % R
% Ser: 0 31 8 39 0 70 0 54 8 0 16 0 0 0 0 % S
% Thr: 8 8 8 0 16 0 8 0 0 8 0 77 0 0 16 % T
% Val: 16 8 16 0 0 0 8 8 16 8 0 8 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 8 0 70 0 % W
% Tyr: 8 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _